Molecular mechanisms of ageing limiting organ maintenance and regeneration

The main objective of this research priority programme (RPP) is the identification and functional characterization of major mechanisms of ageing that limit stem cell function, organ homeostasis and regeneration in response to damage accumulation. To achieve this goal the consortium brings together leading scientists working on molecular mechanisms of ageing in the following three interconnected areas:

  1. Molecular mechanisms of damage accumulation of macromolecules during ageing
  2. Cell-intrinsic checkpoints and alterations of the environment in response to damage accumulation
  3. Systems biology analysis of signalling networks and genetic determinants of ageing

In order to identify major mechanisms of ageing, this consortium has chosen an integrated approach combining research on basic molecular mechanisms of ageing with systems biology. ...more


    © dw-websites     English I Deutsch I Imprint I Contact